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PTEN acts in several pathways that have to do with regulation of cell growth and interacts with proteins that have a major roles in tumor suppression. This was
by pazimzadeh 11y ago
PTEN acts in several pathways that have to do with regulation of cell growth and interacts with proteins that have a major roles in tumor suppression. This was discovered without knowing the actual structure of PTEN, so it should now be easier to develop ways to fiddle with the signaling pathway to our advantage.
Here's an overview of the signaling pathways involved:
http://cl.ly/cuRC http://cl.ly/cuRC
On another note, the interface used to represent biological information (and I'm assuming of other fields) hasn't changed since the invention of the printing press. How lame is that?