Methylene blue improves Complex IV function in mitochondria, so it certainly has a direct effect on mitochondrial function. It's actually used as an antidote t

Methylene blue improves Complex IV function in mitochondria, so it certainly has a direct effect on mitochondrial function. It's actually used as an antidote to several poisons that inhibit mitochondrial function[1]. [1] https://en.wikipedia.org/wiki/Methylene_blue https://en.wikipedia.org/wiki/Methylene_blue