Perhaps you need to do some more research. Downregulation lasts about a year if you're a chronic user/abuser. Even a single bottle of whisky causes downregulati

Perhaps you need to do some more research. Downregulation lasts about a year if you're a chronic user/abuser. Even a single bottle of whisky causes downregulation for something like a week (that's from memory -- I can't find the reference right now). This probably applies more to alcohol/cocaine/opiates rather than LSD.