Also, there's the issue of what sorts of neurological "types" tend to abuse which sorts of drugs. I currently take medication for ADHD which works on the dopam

Also, there's the issue of what sorts of neurological "types" tend to abuse which sorts of drugs. I currently take medication for ADHD which works on the dopamine response and feedback system. Cocaine at least superficially works on similar mechanisms. I remember when I was talking to my doctor prior to being put on the medication and discussing any past recreational drug use. I'm sure that part of this was in order to determine any abuse potential but the doc also mentioned that a lot of times people with atypical dopamine feedback will abuse or "self-medicate" with cocaine. I wonder if more people who gravitate toward heavy cocaine use (or the ones more likely to become habitual cocaine users) do so because they don't get the same sort of feedback and reinforcement from external stimuli as more "neurotypical" people. It's all just conjecture on my part but my experience is that a lot of people who use recreational drugs have their drugs of choice because it's not always just about getting "messed up" but could be because certain tweaks to their neurochemistry are more pleasurable than others.