I'm terribly sorry to hear about your close relative. Given that it is diagnosed as a stage IV GBM, you are likely looking at some combination of clinical trial

I'm terribly sorry to hear about your close relative. Given that it is diagnosed as a stage IV GBM, you are likely looking at some combination of clinical trial based and standard of care therapy. Do not attempt to sort through the confusing web of information on the web or from publications. Many of them need the kind of context that only an academic oncologist can interpret and dont always translate to an increase in individual survival rates in a clinical setting. First and foremost, find an academic cancer center near by, preferably an NCI certified comprehensive cancer center (http://www.cancer.gov/research/nci-role/cancer-centers/find http://www.cancer.gov/research/nci-role/cancer-centers/find). Secondly if your relative is willing and understands the risks, find them an applicable clinical trial to enroll into. The biggest obstacles to effectively treating GBM are the location of the tumor(s), the existence of the blood-brain barrier and the highly aggressive nature of tumor growth. All the best and I really hope you and your relative can find the strength to get through this difficult phase.