Aging is caused by damage accumulation. There are very good ways to model how that works, see for example reliability theory [1]. There is little difference a

Aging is caused by damage accumulation. There are very good ways to model how that works, see for example reliability theory [1]. There is little difference at this level of modeling between a human and a car. It is just a complex system of redundant components subject to breakage. If you repair it well it enough it has an indefinite mean time to failure. The important thing to appreciate about medicine is that no present medicine does anything to repair damage. All advances in medicine and related technologies relevant to control over disease that have led to longer lives across the board have only modestly slowed accumulation of damage. Slowing damage accumulation more deliberately or via engineering metabolism is very hard and the best of approaches can't beat the outcomes of exercise or calorie restriction, they aren't moving the needle any further. I don't expect them to, either. Fortunately, there is the alternative approach of repair, with the outcome of indefinite healthy life spans for sufficiently comprehensive repair. The future is one in which the root cause damage is periodically repaired. Lines of research related to SENS for example, such as senescent cell clearance. Other than some forms of stem cell replacement, there are no implementations of damage repair today, but that will change very rapidly once things get going. [1]: https://en.wikipedia.org/wiki/Reliability_theory_of_aging_and_longevity https://en.wikipedia.org/wiki/Reliability_theory_of_aging_an...