Grasshopper (Rhino) is quite successful for architecture and 3D modeling, but its also tied to the engine. Also see https://news.ycombinator.com/item?id=727467

Grasshopper (Rhino) is quite successful for architecture and 3D modeling, but its also tied to the engine. Also see https://news.ycombinator.com/item?id=7274674 https://news.ycombinator.com/item?id=7274674 for an exhaustive list.