What I was thinking of is that output to a PDF could still be primarily targeted for print, but have the software generate at least 2 pdf documents, one for let

What I was thinking of is that output to a PDF could still be primarily targeted for print, but have the software generate at least 2 pdf documents, one for letter/A4 size paper, and another that is sized closer to 4x6 with minimal margins. Then use deduplication so that it doesn't make the file size much bigger.