4 ms·
Hemispherectomy (removal of one half of the brain) is a treatment for Rasmussen's encephalitis when it's sufficiently severe (or the seizures are not responding
by qiqing 11y ago
Hemispherectomy (removal of one half of the brain) is a treatment for Rasmussen's encephalitis when it's sufficiently severe (or the seizures are not responding to drugs). If done very early in life, the plasticity of brain makes it such that those patients grow up to be normally functioning adults. We believe this is because the regions that specialize for different tasks are able to combine their function on the same half.
Think of, for instance, the "language" areas (Broca's area and Wernicke's area). (The following over-simplified explanation assumes typical right-hand dominant individuals for the sake of brevity.) If you inactivate that area in the left hemisphere (using drugs or transcranial magnetic stimulation), you'll lose "language" processing of data that occurs around 1 Hz (in English, this corresponds to individual words, phonemes; in tonal languages, this includes tones of lexical significance). If you inactivate that area in the right hemisphere instead, you'll lose "language" processing of data that occurs an order of magnitude slower than that (in most languages, this corresponds to pitch and volume changes over the level of the sentence, and can convey prosody information such as speaker intent as well as speaker identity).
Due to specializations like this, hemispherectomies are not performed later in life. You would get symptoms similar to stroke patients. But for all areas, not just language.
- jotm 11y agoSo the brain can function normally without a whole half? That's very interesting. Now I'm wondering how much can be removed without adverse effects :-)
- qiqing 11y agoA non-precise answer: a surprisingly large amount if you're careful about which parts to remove and if you do it really, really early in life. ;) In adults (or even adolescents) though, not as much luck. In the case of hemispherectomies on Rasmussen's patients, you can analogize it as: people are dual-core by default. If you remove one of the cores early enough in life (like <5 yrs old), you can re-route the wiring so that processing can done by one of the cores, and still be pretty much normal. But whatever subtle thing is lost when if we don't do parallel processing like we usually do -- that things is pretty subtle to test for as well.
- redcalx 11y agoPeople can also function without a cerebellum: https://en.wikipedia.org/wiki/Cerebellar_hypoplasia#Signs_and_Symptoms https://en.wikipedia.org/wiki/Cerebellar_hypoplasia#Signs_an...