3 ms·

I won't go down the pharma IP rathole, but I don't think this problem is intractable. There are many inventions that aren't CRISPR where TLO is happy to have t

by jrkelly 11y ago

I won't go down the pharma IP rathole, but I don't think this problem is intractable. There are many inventions that aren't CRISPR where TLO is happy to have the student who invented it run with it. Funding is a much bigger limiter than IP in my experience.

w1ntermute 11y ago
> There are many inventions that aren't CRISPR where TLO is happy to have the student who invented it run with it. And my original point was that Paul Buchheit's request that "If you know great scientists solving important problems, please encourage them to apply" was unrealistic. YC isn't going to get the crème de la crème of scientists or scientific innovations - they're getting what's discarded by the TTOs. To be more precise, nobody's going to get the top scientists (they're going to go right back to their labs) and the biotech VCs are going to get the top innovations (for which they often have an informal licensing option with the inventing professor before the academic research even begins). There's a record amount of funding in biotech right now, but why spread it evenly? Might as well just run dozens of trials in parallel for therapies derived from a single technology.
- jrkelly 11y ago
  You do seem to have it all figured out. I'm glad YC is running the experiment, guess we will need to see how it plays out.
  - w1ntermute 11y ago
    I apologize if I sound overly negative, but I have expended significant time and energy exploring this idea maze (http://cdixon.org/2013/08/04/the-idea-maze/ http://cdixon.org/2013/08/04/the-idea-maze/), only to hit one dead end after another. I left for greener pastures (software), but I wish you and the rest of the YC biotech founders the best of luck.
    - jrkelly 11y ago
      Yeah it is a little ugly in pharma particularly. But I'll take the good luck :) If you come through Boston happy to give you a Ginkgo tour sometime.

by jrkelly 11y ago

w1ntermute 11y ago

> There are many inventions that aren't CRISPR where TLO is happy to have the student who invented it run with it. And my original point was that Paul Buchheit's request that "If you know great scientists solving important problems, please encourage them to apply" was unrealistic. YC isn't going to get the crème de la crème of scientists or scientific innovations - they're getting what's discarded by the TTOs. To be more precise, nobody's going to get the top scientists (they're going to go right back to their labs) and the biotech VCs are going to get the top innovations (for which they often have an informal licensing option with the inventing professor before the academic research even begins). There's a record amount of funding in biotech right now, but why spread it evenly? Might as well just run dozens of trials in parallel for therapies derived from a single technology.

jrkelly 11y ago
You do seem to have it all figured out. I'm glad YC is running the experiment, guess we will need to see how it plays out.
- w1ntermute 11y ago
  I apologize if I sound overly negative, but I have expended significant time and energy exploring this idea maze (http://cdixon.org/2013/08/04/the-idea-maze/ http://cdixon.org/2013/08/04/the-idea-maze/), only to hit one dead end after another. I left for greener pastures (software), but I wish you and the rest of the YC biotech founders the best of luck.
  - jrkelly 11y ago
    Yeah it is a little ugly in pharma particularly. But I'll take the good luck :) If you come through Boston happy to give you a Ginkgo tour sometime.